Etiopatogeneticheskie Podkhody K Lecheniyu Raka Shchitovidnoy Zhelezy

ISBN-13: 9783659522109 / Rosyjski / Miękka / 2014 / 292 str.

Rumyantsev Pavel Olegovich

Opis

Rak shchitovidnoy zhelezy - naibolee chasto vstrechayushchayasya zlokachestvennaya opukhol endokrinnykh organov, lidiruyushchaya po chislu smertelnykh iskhodov sredi zlokachestvennykh endokrinnykh opukholey. V etiologii i patogeneze raka shchitovidnoy zhelezy vazhnuyu rol igraet radiatsionnyy i nasledstvennyy faktory. Anomalno vysokaya zabolevaemost RShchZh na zagryaznennykh vsledstvie chernobylskoy avarii territoriyakh sredi naseleniya, obluchennykh v detskoy i podrostkovom vozraste, sokhranyaetsya po sey den. Proveden sravnitelnyy analiz klinicheskogo techeniya radiatsionno-indutsirovannogo i sporadicheskogo, nasledstvennogo i sporadicheskogo raka shchitovidnoy shchitovidnoy zhelezy. Izuchen vliyanie nasledstvennykh i somaticheskikh mutatsiy izvestnykh onkogenov (RET i BRAF), a takzhe spektra epigeneticheskikh narusheniy pri razlichnykh tipakh kartsinom shchitovidnoy zhelezy. Na mnogochislennom klinicheskom materiale vypolnen mnogofaktornyy analiz vliyaniya prognosticheskikh faktorov na bezretsidivnuyu vyzhivaemost bolnykh vsemi izvestnymi gistologicheskimi tipami raka shchitovidnoy zhelezy. V tselyakh snizheniya riska nevrologicheskikh oslozhneniy khirurgicheskogo lecheniya primenyalsya metod intraoperatsionnogo neyromonitoringa. Optimizirovany algoritmy diagnostiki i lecheniya.

O autorze

V 1993 g. zakonchil lechebnyy fakul'tet MMA im. I.M. Sechenova.1993-98 gg. - klinicheskaya ordinatura i aspirantura v MRNTs (g. Obninsk). 2008-09 gg. - professor Universiteta Nagasaki (Yaponiya). Zanimalsya meditsinskimi posledstviyami Chernobyl'skoy avarii. V nastoyashchee vremya - zamestitel' direktora FGBU ENTs Minzdrava Rossii. Onkolog, radiolog.