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Innate and adaptive immunity play important roles in immunosurveillance and tumor destruction. However, increasing evidence suggests that tumor-infiltrating immune cells may have a dual function: inhibiting or promoting tumor growth and progression. Although regulatory T (Treg) cells induce immune tolerance by suppressing host immune responses against self- or non self-antigens, thus playing critical roles in preventing autoimmune diseases, they might inhibit antitumor immunity and promote tumor growth. Recent studies demonstrate that elevated proportions of Treg cells are present in...

Axial Flux Permanent Magnet (AFPM) brushless machines are modern electrical machines with a lot of advantages over their conventional counterparts. They are being increasingly used in consumer electronics, public life, instrumentation and automation system, clinical engineering, industrial electromechanical drives, automobile manufacturing industry, electric and hybrid electric vehicles, marine vessels and toys. They are also used in more electric aircrafts and many other applications on larger scale. New applications have also emerged in distributed generation systems (wind turbine...

Axial Flux Permanent Magnet (AFPM) brushless machines are modern electrical machines with a lot of advantages over their conventional counterparts. This timeless and revised second edition deals with the analysis, construction, design, control and applications of AFPM machines. The authors present their own research results, as well as significant research contributions made by others.

Extremal Optimization: Fundamentals, Algorithms, and Applications introduces state-of-the-art extremal optimization (EO) and modified EO (MEO) solutions from fundamentals, methodologies, and algorithms to applications based on numerous classic publications and the authors recent original research results. It promotes the movement of EO from academic study to practical applications. The book covers four aspects, beginning with a general review of real-world optimization problems and popular solutions with a focus on computational complexity, such as "NP-hard" and the "phase...