Liposome-Based Drug Delivery Systems

ISBN-13: 9783662493182 / Angielski / Twarda / 2021 / 496 str.

Wan-Liang Lu; Xiang-Rong Qi

Opis

This volume mainly describes the protocols for fabrication of liposomal drug delivery system, and consists of three parts, namely, the advances in liposome-based drug delivery system, the general protocols for fabrication of drug-loading liposomes, and the protocols for preparation of functionalized liposome-based drug delivery system.

Spis treści

;Liposomes in Drug Delivery: Status and Advances; 

Preparation of Drug Liposomes by Thin-Film Hydration and Homogenization; 

Preparation of Drug Liposomes by Reverse-Phase Evaporation; 

Preparation of Drug Liposomes by EDTA Gradient Methods; 

Preparation and Characterization of Drug Liposomes by pH-Gradient Method; 

Preparation and Characterization of Drug Liposomes by Ammonium Sulfate Gradient; 

Preparation and Characterization of Drug Liposomes by Nigericin Ionophore; 

Lipid-Coated Cisplatin Nanoparticles for Insoluble Drug Loading; 

Purification Method of Drug-Loaded Liposome;

Quality Evaluation of Drug-Loaded Liposomes; 

Coupling Methods of Antibodies and Ligands for Liposomes; 

Preparation of Cell Penetrating Peptides-Mediated Targeting Drug Liposomes; 

Preparation and Evaluation of Folate Receptor Mediated Targeting Liposomes; 

Preparation and Evaluation of Rivastigmine Liposomes for Intranasal Delivery; 

Preparation and Evaluation of Integrin Receptor-Mediated Targeting Drug Liposomes; 

Preparation and Evaluation of Biomineral-Binding Antibiotic Liposomes; 

Preparation of Anthracyclines Liposomes for Tumor-Targeting Drug Delivery; 

Preparation and Characterization of pH Sensitive Drug Liposomes; 

Preparation and Characterization of DNA Liposomes Vaccine; 

HER2-Specific PEGylated Immunoliposomes Prepared by Lyophilization/Rehydration Method; 

Fabrication and Evaluation of Dual Peptides-Modified Liposomes Coencapsulating siRNA and Docetaxel; 

Dual-Modified siRNA-Loaded Liposomes for Prostate Cancer Therapy; 

Dequalinium-Mediated Mitochondria-Targeting Drug Liposomes for the Treatment of Drug-Resistant Lung Cancer; 

Preparation of Multifunctional Paclitaxel Liposomes for Treatment of Brain Glioma; 

Preparation of Functional Vincristine Liposomes for Treatment of Invasive Breast Cancer; 

Application of Labeled Liposomes in Imaging and Biodistribution Observation; 

Application of Drug Liposomes in the Hormone Therapy; 

Application of Drug Liposomes in Gene Transfection

O autorze

Prof. Dr. Wan-Liang Lu a principal investigator in State Key Laboratory of Natural and Biomimetic Drugs, Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Systems, and School of Pharmaceutical Sciences, Peking University, Beijing, China

Prof. Dr. Xian-Rong Qi  a principal investigator in Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Systems, Department of Pharmaceutics, and School of Pharmaceutical Sciences, Peking University, Beijing, China