Clinical Research in Oral Health

ISBN-13: 9780813815299 / Angielski / Twarda / 2010 / 392 str.

Giannobile; Ed. William V. Giannobile; Robert J. Genco

Opis

* * Exclusively focused on research within the oral sciences * Provides guidance in all aspects of clinical research, from essential principles to logistics * Clarifies the framework of regulatory issues for researchers and study staff * Presents emerging concepts in translational research.

Recenzje

"This book should be bought by anyone having more than just an interest in research and who is involved in commissioning, funding, planning, undertaking or evaluating research. For everyone else, starting off with more generalised texts and using this book for information on specific subject areas would be more appropriate." (Primary Dental Care and Team in Practice, 1 April 2011)

 

Spis treści

1 Clinical and Translational Research: Implications in the Promotion of Oral Health

William V. Giannobile

 

2 Ethics in Oral Health Research

Elizabeth Ripley, Francis L. Macrina

 

3 Responsibilities of Institutions and Individuals in Clinical Research in the Oral Health Sciences

Gary C. Armitage

 

4 Regulatory Process for the Evaluation of Dental Drugs, Devices and Biologics

Darnell Kaigler, Kay Fuller, William V. Giannobile

 

5 Clinical and Translational Research Grantsmanship: Funding Opportunities and Obtaining Research Support

Bruce L. Pihlstrom, Michael L. Barnett

 

6 Data Management in Oral Health Research

Bruce A. Dye, Jules T. Mitchel

 

7 Hypothesis Testing and Avoiding False–Positive Conclusions

Philippe P. Hujoel

 

8 Outcomes in Oral Health Research

Amid I. Ismail

 

9 Examiner Training: Standardization and Calibration in Periodontal Studies

Niklaus P. Lang, Mary P. Cullinan, Douglas W. Holborow, Lisa J.A. Heitz–Mayfield

 

10 Observational Studies in Oral Health Research

Hal Morgenstern, Woosung Sohn

 

11 Initial Clinical Trials Allow Assessment of Safety, Dosing and Preliminary Efficacy Prior to Large Randomized Controlled Pivotal Studies 

Jules T. Mitchel, Glen Park, Mark Citron, Russ Pagano, Leslie Wisner–Lynch, Samuel E. Lynch

 

12 Phase III Pivotal Clinical Trials: Clinical Decision–making

Norman S. Braveman, Bryan Michalowicz

 

13 Post–Marketing Surveillance

Eugenio D. Beltran–Aguilar, Michael C. Manz

 

14 Dental Practice–Based Research Networks

Donald J. DeNucci and the CONDOR Dental Practice–based Research Networks

 

15 The Technology Transfer Process for Life Science Innovations in Academic Institutions

Robert J. Genco

 

16 Adoption of New Technologies for Clinical Practice

Maxwell H. Anderson

 

17 Publication of Research Findings

James Bader

 

18 The Evidence–base for Oral Health

Helen Worthington, Ian Needleman, Anne–Marie Glenny

 

 

O autorze

William V. Giannobile is a William K. & Mary Anne Najjar Endowed Professor of Dentistry and Biomedical Engineering at the University of Michigan. He is also the Director of the Michigan Center for Oral Health Research and an Associate Editor of the Journal of Periodontology.

Robert J. Genco is a State University of New York Distinguished Professor of Oral Biology, and Microbiology, and Immunology at the University at Buffalo. He is also the Vice Provost and Director of the University at Buffalo Office of Science, Technology Transfer and Economic Outreach, and Editor–in–Chief Emeritus of the Journal of Periodontology.

Brian A. Burt is Professor Emeritus, Department of Epidemiology, and formerly the Director, Program in Dental Public Health, School of Public Health; and Professor Emeritus, School of Dentistry, University of Michigan, Ann Arbor, MI. He was editor of the journal Community Dentistry and Oral Epidemiology from 1997 to 2007.

Blurb

Clinical Research in Oral Health surveys the essentials of clinical research in oral health, anchoring these principles within the specific context of the oral health arena. Addressing research questions exclusively applicable to dentistry and oral health, the book thoroughly illustrates the principles and practice of oral health clinical research. Clinical Research in Oral Health also clarifies the framework of regulatory issues and presents emerging concepts in clinical translation, relating the research principles to clinical improvement.