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​Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women worldwide, accounting for nearly a quarter of the total new cancer cases each year. Of these cases, approximately 15-25% overexpress HER2, a transmembrane RTK kinase that is associated with aggressive tumor growth and poor outcomes. However, in the past decade, survival rates of patients with HER-positive breast cancer have significantly improved due to increased screening, HER2 testing, and breakthrough HER2-targeted drug therapies. Handbook of HER2-Targeted Agents in Breast Cancer...

Este libro pretende destacar varios aspectos sobre el componente genetico de la Enfermedad de Graves, desde los loci involucrados, hasta las herramientas de uso comun en el estudio de la base genetica de esta patologia. El Profesor Garcia-Mayor y la Dra. Alvarez Vazquez son expertos en enfermedades autoinmunes de reconocimiento internacional. Este libro destaca la importancia del componente genetico en la enfermedad, cada vez mas presente en la practica clinica diaria. La comprension de los mecanismos moleculares que subyacen a esta patologia y su correlacion clinica nos abrira nuevas puertas...