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"A compassionate exploration of depression and manic-depression."
-- Forecast

"The most thorough and wide-ranging discussion for lay readers about the interplay of the physical and emotional elements of depression and manic-depression... His presentation is illuminating, and the case histories demonstrate his sensitivity and skill as a clinician.... Whybrow's presentation offers a deeper understanding of, along with a humane and wise approach to these very troubling illnesses."
-- Kirkus Reviews

In this book we present a conceptually integrated approach to disorders of mood. These disorders are defined narrowly as the clinical syndromes of mania and melancholia. The latter is our particular focus, for the simple reason that it is more common and thus more is known about it. Our approach owes much to Adolf Meyer, who first used the term psychobiology. It was he who emphasized in a practical way the importance of the clinician consider ing the joint contribution of psychosocial and biological factors in the genesis of mental disorders. However, until the 1960s, our relative ignorance...

Peter C. Whybrow, director of the Neuropsychiatric Institute at UCLA, grounds the extraordinary achievements and excessive consumption of the American nation in an understanding of the biology of the brain's reward system offering for the first time a comprehensive and physical explanation for the addictive mania of consumerism American Mania presents a clear and novel vantage point from which to understand the most pressing social issues of our time, while offering an informed approach to refocusing our pursuit of happiness. Drawing upon rich scientific case studies and colorful...