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Controlled drug delivery systems have been referred to as delayed action, extended action, gradual action, prolonged release, repeat action, sustained release, depot, timed release systems.This is one of the therapeutic systems of that used locally to obtain a constant drug concentration.Controlled drug delivery occurs when a polymer, whether natural or synthetic, is judiciously combined with a drug or other active agent in such a way that the active agent is released from the material in a predesigned manner.The release of the active agent may be constant over a long period, it may be cyclic...