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Suture use for wound closure dates back to ancient Egypt, with early surgeons experimenting with materials like gold, silk, and animal intestines. By the 19th century, metal threads were tried but caused issues like breakage and infections, leading to the preference for silk. Modern sutures are sterilized using methods such as gamma radiation or ethylene oxide to ensure sterility. They are regulated by the USP and FDA for safety and quality. Sutures are classified by origin, absorbability, and structure. Absorbable sutures, like catgut and synthetic options such as polyglactin, are used for...