Chiral Recognition and Separation Mechanisms

ISBN-13: 9781439852576 / Angielski / Twarda / 2026 / 350 str.

Nelu Grinberg; Nizar Haddad; Shengli Ma

Spis treści

Introduction
Symmetry
Separation of Enantiomers through the Formation of Diastereomers.
Non-chromatographic Methods for the determination of enantiomeric excess.
Mechanism of Chromatographic Chiral Discrimination & Thermodynamics of Chromatographic Chiral Discrimination
Chiral Separation with Taylor Made Polymers
Chiral Separation through Ligand Exchange
Chiral Separation through H-bonds
Chiral Separation through Charge Transfer
Chiral Separation through Inclusion Compounds
Protein Phases and Antibiotic Phases
Polysaccharide Phases
Separation of Enantiomers with Chiral Mobile Phases
Strategies for Method Development for Chiral Separation
Conclusion/Summary and Future possibilities

O autorze

Nelu Grinberg is with Boehringer Ingelheim Pharmaceuticals, in Connecticut, USA.