Comparative Genomics of Membrane Proteins

ISBN-13: 9783838105666 / Angielski / Miękka / 2009 / 76 str.

Niklaus Fankhauser

Opis

In the last five years, a number of genomes from tropical parasites were sequenced. The aim of this project was to perform comparative genomics between different parasites and free-living eukaryotes, with particular emphasis on predicted membrane proteins. From an evolutionary point of view, this provided insights to how different parasites adapted to living within a host. From a pharmacological point of view, the project supported the identification of candidate virulence factors, antigens, and drug targets in parasites. The first part focuses on GPI-anchored proteins, the second one on repeat-containing membrane proteins, and the third part on transporter families.

O autorze

Niklaus Fankhauser, Dr. phil.-nat.: Master of Science in Biology
with Major in Cell Biology at the University of Bern in 2003. PhD
in Bioinformatics in 2007 with Prof. Pascal Maeser. Currently
Postdoc at the ETH Zurich working for SystemsX.