Chimerism: A Clinical Guide

ISBN-13: 9783319898650 / Angielski / Twarda / 2018 / 200 str.

Nicole L. Draper

Opis

This text provides a comprehensive, up-to-date review of chimerism. The first part of the volume presents the causes of chimerism, specifically focusing on fertilization and early embryonic errors, pregnancy and multiple gestations, and transplantation and transfusion.

Recenzje

"The purpose is to provide a single source of the 'current understanding of chimerism.' This worthy objective is well met by this book. ... This book would be of interest to anyone working in blood bank/transfusion services or molecular genetic testing, general anatomical pathologists and specialists in forensics, autoimmune and/or obstetrical pathology. ... This is a fantastic book and a fascinating read. You will quickly get up to speed in an esoteric area which surprisingly impacts many aspects of medicine." (Valerie L. Ng, Doody's Book Reviews, November, 2018)

Spis treści

Part I: Causes of Chimerism in Humans

Chapter 1: Fertilization and Early Embryonic Errors

Nicole L. Draper, Kristy Crooks

Chapter 2: Pregnancy and Multiple Gestations

Linda Marie Randolph, Ramen H. Chmait

Chapter 3: Transplantation and Transfusion

Joel N. Kniep

Part II: Clinical Identification and Consequences of Chimerism

Chapter 4: Relationship Testing and Forensics 

Kayla Sheets, Robert Wenk

Chapter 5: Prenatal Genetic Testing and Screening

Ignatia B. Van den Veyver

Chapter 6: Blood Typing Discrepancies

Opal L. Reddy, Dawn C. Ward, Andrea M. McGonigle

Chapter 7: Hematopoietic Stem Cell Donor Selection and Graft-Versus-Host Disease

Alexa J. Siddon, Christopher A. Tormey

Chapter 8: Passenger Lymphocyte Syndrome

Nicole L. Draper, Jamie E. Kallan

Chapter 9: Chimerism: A Clinical Guide to Tolerance Induction

Andrea R. Merchak, Anita Chhabra, Joseph Leventhal, Suzanne T. Ildstad

Chapter 10: Autoimmune Disease

Nathalie Lambert 

Chapter 11: Cancer

Valentina Cirello, Laura Fugazzola

O autorze

Nicole L. Draper, MD

University of Colorado School of Medicine

Department of Pathology

Aurora, CO 

USA

Blurb

This text provides a comprehensive, up-to-date review of chimerism. The first part of the volume presents the causes of chimerism, specifically focusing on fertilization and early embryonic errors, pregnancy and multiple gestations, and transplantation and transfusion. The second part of the volume outlines clinical identification and consequences of chimerism. Chapters in this section focus on the effects of chimerism on testing in relationship determination and forensics, prenatal genetic testing and screening, and blood and HLA typing. This part also reviews new data concerning matching donors and recipients for transplantation, while outlining the risks of transplantation, such as graft-vs-host disease and passenger lymphocyte syndrome.  Additionally, evidence on the role of chimerism in autoimmune disease and cancer is presented.  

Written by experts in the field, Chimerism: A Clinical Guide is a valuable resource for clinicians and researchers that will help guide patient management and stimulate investigative efforts.