Textbook of Interventional Cardiovascular Pharmacology

ISBN-13: 9780367389024 / Angielski / Miękka / 2019 / 680 str.

Nicolas Kipshidze; Jawad Fareed; Patrick W. Serruys

Opis

While all interventional cardiologists have access to pharmacopeial texts and databases, it is essential that they remain up to date on the growing number of pharmacological agents in the armamentarium. In addition, they must be well-versed as to the ideal agent or combination of agents in a host of differing patient situations. This volume offers complete coverage of all the major pharmacological therapies used in treating the cath lab patient. The book brings practical, personal insight from those actively involved in interventional cardiology.

Spis treści

SYSTEMIC AND ENDOLUMINAL THERAPY. Principles of Antithrombotic Therapy. Principles of Antiplatelet Therapy. Glycoprotein Iib/Iiia Inhibitors. ADP Receptor Inhibitors. Phosphodiesterase Inhibitors. Heparin, Low Molecular Weight Heparin, Heparinoids. Direct Thrombin Inhibitors. Parenteral Direct Antithrombin. Oral Antithrombin Drugs. Antixa Drugs. Combined Anticoagulant and Antiplatelet Therapy. Thrombolytics-Fibrinolytic Therapy. Resistance to Anti-Platelet Drugs. Fibrin Glue and Related Sealants. Lipid-Lowering Agents. Antihypertensive Agents. Homocysteine Regulators. Role of Systemic Anti-Restenotic Drugs and Results of Current Clinical Trials. Oral Anti-Neoplastic Agents For Prevention of Restenosis. Antioxidants. Iron Chelation: Deferoxamine and Beyond. LOCAL THERAPY. Principles of Local Catheter Delivery. Stent-mediated Local Drug Delivery. Brachytherapy. Platforms of Local Delivery. Polymers. Biopolymers. Classification of Anti-restenotic Drugs. Anti-proliferative Compounds (Taxol, Actinomycin, Vasenoids) and Mechanisms of Action. Anti-inflammatory Drugs (Sirolimus, Steroids) and Mechanisms of Action. Anti-migratory Drugs and Mechanisms of Action. Anti-angiogenesis Drugs and mechanism of action. Vasculoprotective Approach for Restenosis. Nitric Oxide Donors. Estradiols. VEGF. Gene Therapy. Antisense Approach. Principles of PDT. Therapeutic Angiogenesis.Characteristics of Different Delivery Devices. Periadventitial Delivery of Drugs. Angiogenesis and Myogenesis. Growth Factor Therapy. Stem Cell Transplantation. Results of Recent Clinical Trials. ADJUNCTIVE PHARMACOTHERAPY. The Heart Failure Patient. The Acute Coronary Syndrome Patient 48. The Diabetic Patient. The Stroke Patient. Atrial Fibrillation . Pregnancy and PCI. Contrast-induced Nephropathy after PCI . Erectile Dysfunction. Carotid Stenting. Peripheral Vascular Disease. Drug Interaction in Patients Undergoing Cardiovascular and Vascular Interventions. Newer Pharmacologic Approaches Targeting Receptors an

O autorze

Nicholas N. Kipshidze, Jeffrey W. Moses, Jawed Fareed, Patrick W. Serruys