Integrated View of Reactive Oxygen Species, Oxidative Stress in Ageing : Basic Mechanism, Functional Effect and Possible Biomarkers

ISBN-13: 9783659285516 / Angielski / Miękka / 2012 / 64 str.

Fatema Binte Hafiz; Md. Anwarul Haque; Nayeem Md. Towfique

Opis

1. Introduction Types of reactive oxygen species (ROS) Sources Structure Mechanism of ROS generation p53,oxidative stress and ROS. 2. Oxidative stress and free radical damage Oxidative lipid damage Oxidative DNA damage Oxidative protein damage Role of ROS in cell signaling Aberrant regulation of redox-sensitive signal pathway Molecular mechanism of age-related diseases. 3. Antioxidant defense Antioxidant therapy Oxidative modification of protein and possible biomarkers. 4. Specific pathways transduced by ROS and ROS-induced apoptosis will provide opportunities to impact both life span, Age related-diseases and design the chemotherapeutics for humans.

O autorze

Fatema Binte Hafiz has completed Bachelor of Science (Honors) in Biotechnology and Genetic Engineering from Islamic University,Bangladesh. She has intense interest to carry out higher research on anti-ageing medicine development and related molecular biology studies.