Analysis and Biological Evaluation of Jordanian Olive Trees Leaves

ISBN-13: 9783639350210 / Angielski / Miękka / 2011 / 176 str.

Muneer Abuismail

Opis

Master Thesis in Applied Chemical Science, it Includes studing 27 different olive tree cultivars leaves ethanolic extracts in terms of their total phenolic content, antioxidant activity, toxicity to brine shrimps, anticancer activity (cell cycle analysis, cell death assay, MTT test), safety on normal cells (MTT test), LC-MS anlysis and quntification for some of their chemical constituents like Oleuropein, Oleanolic acid, Erythrodiol with its isomer Uvaol, Quercetin, Rutin. investigation of the presence of Resveratrol and Salicin qualitatively and quantitatively using LC-MS anlysis , studing the correlation between each constituent concentration in the extracts and their toxicity to brine shrimps also their correlation with anticancer activity on 7 cancer cell lines (MCF- 7, MDA-MB-231, C32, MV3, SW480, SW620, HCT-116), LC- MS(-)ESI,(+)APCI finger print of the most potent anticancer extracts.

O autorze

Jordanian chemist was born in 1978 at the city of Irbid-Jordan, finished high school in 1996 and studied Chemistry at the Jordan University of Science and Technology, worked as teacher of Chemistry,started his graduat study for the Master Degree in Chemistry in 2007 and finished it in 2011 with an invention related to cancer treatment.