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Since its identification by Sir Henry Dale a century ago, histamine has become one of the most important multifunctional biogenic amines in the field of biomedicine. The pharmacologic effects of histamine are mediated through four types of membrane histamine receptors; H1R, H2R, H3R and H4R, which are all heptahelical G-protein-coupled receptors. It has been known to play the broadest spectrum of activities in various physiological and pathological conditions including cell proliferation, differentiation, hematopoiesis, embryonic development, regeneration, wound healing, aminergic...

Since its identification by Sir Henry Dale a century ago, histamine has become one of the most important multifunctional biogenic amines in the field of biomedicine. The pharmacologic effects of histamine are mediated through four types of membrane histamine receptors; H1R, H2R, H3R and H4R, which are all heptahelical G-protein-coupled receptors. It has been known to play the broadest spectrum of activities in various physiological and pathological conditions including cell proliferation, differentiation, hematopoiesis, embryonic development, regeneration, wound healing, aminergic...

The Hidden Land has a lot of twists and turns, the story starts with a peaceful land called Cassandra. Soon, Cassandras residents begin to be abducted by creatures known as Gangrians. A giant with a short temper and to make things worse they have pets called Thoraxs. Now when four teenagers end up in the Gangrians land, Gryon, things get messy and confusing. Two of them are taken by the Gangrians and the other two have to safe them, luckily, a little Gangrian comes to their aid with the ability to speak. With its help and the Betrayers who was the Leader of this land, the two teenagers set...