Regulación de la señalización del receptor de etileno por RTE : RTE1 etileno

ISBN-13: 9786139406340 / Angielski

Maximo Rivarola

Opis

Ethylene is an important regulator of plant growth, development and responses to environmental stresses. Genetic analyses have shown that the RTE1 locus is a positive regulator of ETR1. RTE1 encodes a novel protein of unknown molecular function, and is conserved in plants, animals and some protists. The goal of this research was to analyze the mechanisms involved in the regulation of ethylene receptor signaling by RTE1 and to enhance our understanding of the conserved cellular role of RTE1. Here we tested hypotheses for how RTE1 affects ETR1 and is specific to only ETR1, not the other ethylene receptor isoforms. We show that ETR1 and RTE1 gene expression patterns partially overlap and that the ETR1 receptor co-localizes with RTE1 within the cell. Moreover, RTE1 has no effect on ETR1 protein abundance or subcellular localization suggesting other mechanisms to regulate ETR1. We provide supporting evidence that RTE1 affects ETR1 signaling by restoring signaling of a non-functional ETR1 in an rte1 null through changes in ETR1 conformation(s).

O autorze

Rivarola, Maximo
Biólogo Molecular egresado de la Universidad de BuenosAires, Argentina (2002). Doctorado en Biología Celular y Genética Molecular de la Universidad de Maryland, Facultad de Ciencias Naturales. CollegePark, MD. EEUU (2008).Investigador Adjunto de Conicet (2011-actualidad). Profesor Adjunto UADE.