Papillomaviruses in Human Cancer: The Role of E6 and E7 Oncoproteins

ISBN-13: 9781475761290 / Angielski / Miękka / 2013 / 173 str.

Massimo Tommasino

Opis

Human Papillomavirus has been associated with cancer of the anogenital tract, oral cavity and skin. Two early viral proteins, E6 and E7, play a key role in the malignant transformation of the cell. This book covers different aspects of these two viral oncoproteins. In particular, it focuses on their mechanism in the induction of cellular proliferation and malignant transformation.

Spis treści

1. Human Papillomaviruses and Cancer: A Retrospective.- 2. Regulation of E6 and E7 Oncogene Transcription.- 3. E6 Protein.- 4. E7 Protein.- 5. Immunological Aspects of the E6 and E7 Oncogenes: Tools for Diagnosis and Therapeutic Intervention.