1. Introduction on medical rehabilitation 2. Orthosis applications in medical rehabilitation 3. Mechanical fundamental and design of the active orthosis 4. Electrical, electronic, and digital instrumentation of active orthosis 5. Automatic control design of the active orthosis 6. Artificial intelligence applications on active orthosis development 7. Clinical evaluations of active orthosis: protocols, testing, and validation 8. Active orthosis for medical rehabilitation of lower limbs 9. Active orthosis for medical rehabilitation of upper limbs 10. Active orthosis for medical rehabilitation of chest and back 11. Active orthosis for medical rehabilitation of neck 12. Ethical, medical, and legal implications of active orthosis 13. Cyberphysical systems interpretation of active orthoses