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"Immunopharmacology," why not "pharmacoimmunology"? Professor H. O. Schild University College London, 1962 An intact immune response is essential for survival, as is evidenced by the various innate immune deficiency syndromes and by the emergence of the acquired immune deficiency syndrome (AIDS) as a pandemic during the last decade. Substances which stimulate the immune response might contribute to the therapy of AIDS and its precursor, AIDS-related syndrome, as well as of other clinical conditions in which immune responses can be diminished, such as carcinoma and infections. In other...

Volume 2 of the 5th Edition of the Handbook of Obesity spotlights on clinical applications for evaluation, diagnosis, prevention, and treatment of obesity. It covers on the several major developments occurred between the previous and the new edition, including the effect of SARS-CoV-2 on people with obesity, the concept of “Precision Medicine”, and new medications approved by USFDA aiding patients with obesity weight loss of 15 to 20%. This volume is structured into 5 parts: Part 1 provides insights from evolution on changes in diet and physical activity, and the implications and...

Research on massive stars is undergoing a period of rapid progress, with long-held convictions being shown to be incomplete. While these stars are relatively few in number, they are the main driver of chemical and dynamical evolution in galaxies through their stellar winds and explosive deaths in core-collapse supernovae. Furthermore the impact of massive stars is widely recognized in many areas, as they are often used as tools to interpret the conditions and processes arising in different environments. In parallel, the development of new instrumentation, analysis techniques and dedicated...