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Hepatocellular carcinoma (HCC) is a common tumor type arising from several distinct etiologies. It is usually diagnosed late and is difficult to treat. This volume presents an overview of selected aspects of HCC pathogenesis, and research aimed at developing diagnostic biomarkers. It points to a number of putative therapeutic targets, including signal transduction pathways, metabolic and epigenetic alterations in tumor cells, the tumor microenvironment, the gut microbiome, and functions of immune effector cells. Given the multi-step nature of most cancers, including HCC, future drug...

This volume contains the papers presented at the f th workshop on Job SchedulingStrategiesforParallelProcessing, whichwasheldinconjunctionwith the IPPS/SPDP 99conference in San Juan, Puerto Rico, on April 16, 1999.The papers have been through a complete refereeing process, with the full version beingreadandevaluatedbyv etosevenmembersoftheprogramcommittee.We would like to take this opportunity to thank the program committee, Andrea Arpaci-Dusseau, Stephen Booth, Allen Downey, Allan Gottlieb, Atsushi Hori, PhilKrueger, RichardLagerstrom, MironLivny, VirginiaLo, ReaganMoore, Bill Nitzberg,...