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Chromosomes have structure, determined by the interactions of proteins with DNA, and chromosomes have functions, in particular, replication of DNA and transcription of messenger RNA. Chromosome structure and function are not separate topics, since chromosome organization pro foundly influences the activity of the genome in replication and transcrip tion. This is especially clear for higher cells, including human cells, in which chromatin fibers are created by the binding of histone proteins to the DNA, and folding of the fibers produces mitotic chromosomes and interphase nuclei. The intricate...

Molecular biology and genetics techniques now dominate viral research in attempts to cure diseases such as AIDS. Viral Genome Methods is a practical guide to the newest molecular techniques, providing step-by-step protocols to be used in the laboratory. Recognized authorities and pioneers in viral research pass on their expertise to you.

Reflecting critically on the discipline of African American studies is a complicated undertaking. Making sense of the black American experience requires situating it within the larger cultural, political-economic, and ideological dynamics that shape American life. This volume moves away from privileging racial commonality as the fulcrum of inquiry and moves toward observing the quality of the accounts scholars have rendered of black American life. This book maps the changing conditions of black political practice and experience from Emancipation to Obama with excursions into the Jim Crow era,...

Reflecting critically on the discipline of African American studies is a complicated undertaking. Making sense of the black American experience requires situating it within the larger cultural, political-economic, and ideological dynamics that shape American life. This volume moves away from privileging racial commonality as the fulcrum of inquiry and moves toward observing the quality of the accounts scholars have rendered of black American life. This book maps the changing conditions of black political practice and experience from Emancipation to Obama with excursions into the Jim Crow era,...