1. Introduction to human genetics 2. Disease in a dish: Cellular models to understand human conditions 3. Tiny models to answer big questions: The worm and the yeast as tools in human genetics research 4. Understanding human genetic disease with the fly 5. Studying human genetic variation in zebrafish 6. The mouse, a key model organism for biomedical research 7. Crispr/Cas technology 8. Integrative modeling and novel technologies in human genomics 9. Models to understand human genomics, final considerations