Zebrafish Model for Biomedical Research

ISBN-13: 9789811652165 / Angielski / Twarda / 2022

Prasan R. Bhandari; Kala Kumar Bharani; Amit Khurana

Spis treści

1 ABCD of Zebrafish Culture.- 2 Zebrafish: a model organism to understand tumor angiogenesis mechanism.- 3 Zebrafish as a xenotransplantation model for studying cancer biology and cancer drug discovery.- 4 Zebrafish Models for Screening of Metabolic diseases.- 5 Role of Zebrafish as an experimental model for renal disorders.- 6 Evolution of Zebrafish As A Novel Pharmacological Model in Endocrine Research.- 7 Zebrafish as a versatile model for cancer research.- 8 Zebrafish as an Indispensable tool for Infectious diseases & Immune modulatory studies.- 9 Common models for cancer research.- 10 Zebrafish model for biomedical research.- 11 Zebrafish Model for Biomedical Research: Creating Waves in Ocean of Evidence.- 12 Zebrafish as a novel pharmacological screening model for drug discovery and development against hematological disorders.- 13 Zebrafish-a Metamorphosis in Ophthalmological Research: A Literature Review.- 14 Zebrafish: A potential  preclinical model for neurological research in modern biology.- 15 Zebrafish Screening for Skin Diseases.- 16 Growing importance of Zebrafish in translational neuroscience.- 17 Supporting the next generation of risk assessment in toxicology: the design of AOPs anchored on the alternative model zebrafish.- 18 Zebrafish: a novel model in Psychopharmacological research.- 19 Pharmacological modeling of gastrointestinal disorders in zebrafish for drug discovery and development.- 20 Zebra Fish Models for Liver Diseases.- 21 Zebrafish Model for Neurotoxic Drug Screening: Methodologies and Protocols.

 

O autorze

Dr. Prasan R Bhandari is currently serving as professor and head in the department of pharmacology at Symbiosis Medical College for Women at Pune. He has obtained his medical degree from one of the oldest and premier institutes of India i.e. Grant Medical College & J.J.Group of Hospitals, Mumbai. He has received his post-graduation in M.D Pharmacology from the academically renowned institute Topiwala National Medical College, B. Y. L. Nair Charitable Hospital, Mumbai. He has over 25 years of academic, teaching, research, administrative as well as industry experience. He has published several articles in both national and international journals. He has served as an examiner in several universities for both postgraduate and undergraduate medical, dental, physiotherapy and other allied paramedical students.

Prof. Kala Kumar Bharani is currently working as professor and head of the department of veterinary pharmacology and toxicology at the College of Veterinary Science, Warangal, Telangana. Prof. Bharani graduated from the Andhra Pradesh Agricultural University (APAU), Hyderabad, India and completed his PhD from the Sri Venkateswara Veterinary University (SVVU) Tirupati. He is a recipient of the Telangana State Best Teachers Award, Dr Lalitha Kameswaran Award and Dr S. B. Pandey Award. Currently, he is serving as the secretary-general of the Indian Pharmacological Society (IPS). Prof. Bharani has published more than 50 peer-reviewed research and review articles.

Dr. Amit Khurana is working as a research scientist at the Centre for Biomedical Engineering (CBME), Indian Institute of Technology (IIT) New Delhi, India. Dr. Khurana graduated from the Delhi Institute of Pharmaceutical Sciences and Research (DIPSAR), University of Delhi, India. He obtained PhD in pharmacology and toxicology from the National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, India. He is a recipient of multiple prestigious fellowships and awards like the DST-DAAD Fellowship, DBT-CNPq Indo-Brazil Fellowship, PC Dandiya Young Scientist Award of the Indian Pharmacological Society (IPS) and Merit Award from the Delhi Pharmacy Council. His research interests include nanomedicine, novel therapeutics for gastroenterological and fibrotic disorders. He has authored more than 40 research and review publications and has contributed to more than 10 book chapters (Elsevier, Springer Nature, CRC Press).

Blurb

This book provides the latest information on the significance of zebrafish as an ideal model for researching the biomedical field, with references. This book also focused on the evidence of zebrafish as a model in cardiovascular, neurologic, psychiatric and metabolic research. In addition, the book also includes the research carried out on zebrafish in hepatic, renal, ophthalmic, and ENT related areas. Contributed chapters come from the most prominent laboratories working in this field, which provides a unique perspective on zebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specific zebrafish models including specific research in the area of skin disorders, endocrine diseases, nutritional disorders, gastrointestinal, hematological disorders and cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text on zebrafish and its suitability for modeling various diseases, providing a critical resource on the potential attributes of the zebrafish as a pharmacological model. In terms of scope, this book is a useful tool for young researchers, professors and pharmaceutical scientists for understanding the significance of zebrafish as an emerging pharmacological model that can significantly aid in the process of drug discovery and development.