Partially Substituted Calix[4]arene Derivatives : Synthesis, Characterisation and Binding Properties

ISBN-13: 9783659964121 / Angielski

José Antonio Villanueva Salas

Opis

This thesis concerns the synthesis, characterisation and binding properties of partially substituted calix[4]arene amino derivatives in non-aqueous media. Thus, 5,11,17,23 - tetrakis - (1,1-dimethyl ethyl) - 25,27 - bis - [2 -(diethyl amino) ethoxy] calix[4]arene (L3) was structurally (1H NMR and X-ray crystallography) characterised and its interaction with metal cations and the proton has been investigated by several techniques. Information about the active sites of interaction of this ligand with ionic species was obtained from 1H NMR measurements. Conductance measurements were used to establish the composition of the metal-ion complexes in protic and dipolar aprotic solvents. Potentiometric measurements using two electrodes systems (mercury and glass electrodes) were carried out to determine quantitatively the strength of ligand-ion interactions in acetonitrile at 298.15 K.

O autorze

Villanueva Salas, José Antonio
José Antonio Villanueva Salas - B. Sc. Pharmacy and Biochemistry. Thermochemistry Laboratory, School of Biomedical and Molecular Sciences, University of Surrey, United Kingdom.