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For Albert Einstein, 1905 was a remarkable year. It was also a miraculous year for the history and future of science. In six short months, from March through September of that year, Einstein published five papers that would transform our understanding of nature. This unparalleled period is the subject of John Rigden's book, which deftly explains what distinguishes 1905 from all other years in the annals of science, and elevates Einstein above all other scientists of the twentieth century.

Rigden chronicles the momentous theories that Einstein put forth beginning in March 1905: his...

Seduced by simplicity, physicists find themselves endlessly fascinated by hydrogen, the simplest of atoms. Hydrogen has shocked, it has surprised, it has embarrassed, it has humbled--and again and again it has guided physicists to the edge of new vistas where the promise of basic understanding and momentous insights beckoned. The allure of hydrogen, crucial to life and critical to scientific discovery, is at the center of this book, which tells a story that begins with the big bang and continues to unfold today.

In this biography of hydrogen, John Rigden shows how this singular atom,...

Typical travel guides have sections on architecture, art, literature, music and cinema. Rarely are any science-related sites identified. For example, a current travel guide for Germany contains one tidbit on science: Einstein is identified as the most famous citizen of Ulm. By contrast, this travel guide walks a tourist through Berlin and identifies where Max Planck started the quantum revolution, where Einstein lived and gave his early talks on general relativity, and where, across the street, Einstein s books were burned by the Nazis. Or, if you are walking in Paris, this guide tells you...

Proteins lie at the heart of almost all biological processes and have an incredibly wide range of activities. Central to the function of all proteins is their ability to adopt, stably or sometimes transiently, structures that allow for interaction with other molecules. An understanding of the structure of a protein can therefore lead us to a much improved picture of its molecular function. This realisation has been a prime motivation of recent Structural Genomics projects, involving large-scale experimental determination of protein structures, often those of proteins about which little is...

This book is about protein structural bioinformatics and how it can help understand and predict protein function. It covers structure-based methods that can assign and explain protein function based on overall folds, characteristics of protein surfaces, occurrence of small 3D motifs, protein-protein interactions and on dynamic properties. Such methods help extract maximum value from new experimental structures, but can often be applied to protein models. The book also, therefore, provides comprehensive coverage of methods for predicting or inferring protein structure, covering all...