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The book provides an updated overview of molecular analysis of human tissues, and the impact this analysis has on diagnosis and prognosis of human diseases. Special emphasis is placed on human cancer and the future directions of the field. Methods of handling clinical tissue samples, including the impact of handling on subsequent molecular analysis, are also discussed. In addition, detailed protocols for molecular analysis of DNA, RNA and protein, with special emphasis on molecular analysis of highly complex human tissue samples containing mixtures of cell populations, are provided.

This concise introduction offers students and researchers an overview of the discipline that connects genetics and evolution. Addressing the theories behind population genetics and relevant empirical evidence, John Gillespie discusses genetic drift, natural selection, nonrandom mating, quantitative genetics, and the evolutionary advantage of sex. First published to wide acclaim in 1998, this brilliant primer has been updated to include new sections on molecular evolution, genetic drift, genetic load, the stationary distribution, and two-locus dynamics. This book is indispensable for...

Designed to assist librarians with collection development, this work identifies, describes, and evaluates more than 800 significant bibliographies of children's and young adult materials. Emphasis is on print and nonprint works published from 1986 through 1996, with some earlier but still useful publications. Special attention is given to such electronic media as CD-ROMs and the Internet. The book is arranged by broad subjects with essential and highly recommended titles noted. Annotations indicate scope of a work, purpose, contents, suitability, special features, and general usefulness. A...