Preface xxviiContributors xxixPart I Introduction 11 How We Came to Have Lungs and How Our Understanding of Lung Function has Developed 3Part II Foundations 212 Getting Started 233 Development and Functional Anatomy of the Respiratory System 33Sungmi Jung and Richard Fraser4 Body Size and Anthropometric Measurements 455 Numerical Interpretation of Physiological Variables 57J. Martin Bland6 Basic Terminology and Gas Laws 75Adrian Kendrick7 Basic Equipment and Measurement Techniques 91Brendan G. Cooper8 Respiratory Surveys 117Peter G.J. Burney9 The Application of Analytical Technique Applied to Expired Air as a Means of Monitoring Airway and Lung Function 129Paolo Paredi and Peter BarnesPart III Physiology and Measurement of Lung Function 14910 Chest Wall and Respiratory Muscles 151Andre De Troyer and John Moxham11 Lung Volumes 17712 Lung and Chest Wall Elasticity 187G. John Gibson13 Forced Ventilatory Volumes and Flows 203Riccardo Pellegrino14 Theory and Measurement of Respiratory Resistance 217Jason H.T. Bates15 The Control of Airway Function and the Assessment of Airway Calibre 231Eric Derom16 Ventilation, Blood Flow, and Their Inter-Relationships 259G. Kim Prisk17 Transfer of Gases into the Blood of Alveolar Capillaries 301Eric Derom and Guy F. Joos18 Transfer Factor (Tl) for carbon monoxide (CO) and nitric oxide (NO) 313Colin D.R. Borland and Mike Hughes19 Oxygen 353Dan S. Karbing and Stephen E. Rees20 Carbon Dioxide 377Erik R. Swenson21 Control of Respiration 389Bertien M.-A. Buyse22 The Sensation of Breathing 407Mathias Schroijen, Paul W. Davenport, Omer Van den Bergh, and Ilse Van Diest23 Breathing Function in Newborn Babies 423Urs P. Frey and Philipp LatzinPart IV Normal Variation in Lung Function 43524 Normal Lung Function from Childhood to Old Age 437Andrew Bush and Michael D.L. Morgan25 Reference Values for Lung Function in White Children and Adults 46326 Reference Values for Lung Function in Non-White Adults and Children 499Part V Exercise 51727 Physiology of Exercise and Effects of Lung Disease on Performance 51928 Exercise Testing and Interpretation, Including Reference Values 55329 Assessment of Exercise Limitation, Disability, and Residual Ability 57730 Exercise in Children 587Andrew BushPart VI Breathing During Sleep 59531 Breathing During Sleep and its Investigation 597Joerg SteierPart VII Potentially Adverse Environments 61532 Hypobaria 617James Milledge33 Immersion in Water, Hyperbaria, and Hyperoxia Including Oxygen Therapy 639Einar Thorsen34 Effects of Cold and Heat on the Lung 653Malcolm Sue-ChuPart VIII Lung Function in Clinical Practice 66135 Strategies for Assessment of Lung Function 663James Hull36 Patterns of Abnormal Lung Function in Lung Disease 673William Kinnear37 Lung Function in Asthma, Chronic Obstructive Pulmonary Disease, and Lung Fibrosis 681Wim Janssens and Pascal Van Bleyenbergh38 Lung Function in Specific Respiratory and Systemic Diseases 697Stephen J. Bourke39 Pulmonary Rehabilitation 729Sally Singh40 Lung Function in Relation to Surgery, Anaesthesia, and Intensive Care 737Goran HedenstiernaIndex 751
John Cotes, PhD, (deceased), was a respiratory physiologist who played a key role in the conquest of Everest in 1953. He also played prominent roles in the European Respiratory Society, the Thoracic Society, and the Association of Respiratory Technicians and Physiologists, and was an honorary fellow of the Faculty of Occupational Medicine.Robert L. Maynard, CBE, FRCP, FRCPath, is an Honorary Professor of Environmental Medicine at the University of Birmingham, Birmingham, UK.Sarah J. Pearce, FRCP, is Formerly Consultant Physician at County Durham and Darlington NHS Foundation Trust, Darlington, UK.Benoit B. Nemery, MD, PhD, is Professor of Toxicology & Occupational Medicine for the Faculty of Medicine at the Department of Public Health and Primary Care, KU Leuven, Belgium.Peter D. Wagner, MD, is Distinguished Professor of Medicine & Bioengineering at the University of California, San Diego, CA, USA.Brendan G. Cooper, PhD, FERS, FRSB, is Consultant Clinical Scientist in Respiratory and Sleep Physiology at University Hospital Birmingham and holds an Honorary Professorship in Respiratory & Sleep Physiology at the University of Birmingham, Birmingham, UK.
