Part I. Principles of Oncology: 1. Interventional oncology: the fourth pillar of cancer care Michael C. Soulen and Jean-Francois H. Geschwind; Part II. Principles of Image-Guided Therapies: 2. Principles of radiofrequency and microwave tumor ablation Anthony M. Esparaz, S. Nahum Goldberg and Muneeb Ahmed; 3. Principles of irreversible electroporation Govindarajan Srimathveeravalli and Stephen B. Solomon; 4. Principles of high intensity focused ultrasound Aradhana M. Venkatesan and Bradford J. Wood; 5. Principles of tumor embolotherapy and chemoembolization Hwan Jun Jae, Jae Hyung Park and Jin Wook Chung; 6. Principles of radioembolization Vanessa L. Gates, Riad Salem and Robert J. Lewandowski; 7. Principles of intraarterial infusional chemotherapy in the treatment of liver metastases from colorectal cancer Fidel David Huitzil Melendez and Nancy Kemeny; 8. Imaging in interventional oncology: role of image guidance Francois Cornelis and Stephen B. Solomon; 9. Novel developments in MR assessment of treatment response after locoregional therapy Kelly Fabrega-Foster, Neda Rastegar, Jean-Francois H. Geschwind and Ihab R Kamel; Part III. Organ-Specific Cancers - Primary Liver Cancers: 10. Assessment and triage of hepatocellular carcinoma Riccardo Lencioni; 11. Image guided ablation of hepatocellular carcinoma Laura Crocetti, Maria Clotilde Della Pina, Dania Cioni and Riccardo Lencioni; 12. Embolization of liver tumors: anatomy Hyo-Cheol Kim and Jin Wook Chung; 13. Conventional chemoembolization and chemoembolization with drug-eluting beads: technique and future potential Julius Chapiro, Florian Nima Fleckenstein, Lynn Jeanette Savic and Jean-François H. Geschwind; 14. 90Yttrium radioembolization for hepatocellular carcinoma Ryan M. Hickey, Riad Salem and Robert J. Lewandowski; 15. Image-guided therapy of intrahepatic cholangiocarcinoma Michael C. Soulen and William S. Rilling; Part IV. Organ-Specific Cancers - Liver Metastases: 16. Colorectal masses: ablation Elena N. Petre, Stephen B. Solomon and Constantinos T. Sofocleous; 17. Assessment, triage and chemoembolization for colorectal liver metastases Michael C. Soulen, Govindarajan Narayanan and Ursina Teitelbaum; 18. Radioembolization for colorectal liver metastases Lourens Bester, Baerbel Meteling and David Boshell; 19. Assessment, triage and liver-directed therapies for neuroendocrine tumor metastases Terence P. Gade and Michael C. Soulen; 20. Preoperative portal vein embolization David Li and David C. Madoff; Part V. Organ-Specific Cancers - Extrahepatic Biliary Cancer: 21. Extrahepatic biliary cancer: stenting, brachytherapy and photodynamic therapy Vlastimil Valek and Tomas Andrasina; Part VI. Organ-Specific Cancers - Renal Cell Carcinoma: 22. Management of small renal masses Mansi A. Saksena, Debra A. Gervais, Michael C. Soulen and Peter R. Mueller; 23. Embolotherapy in the management of renal cell carcinoma Ricardo Garcia-Monaco; Part VII. Organ-Specific Cancers - Chest: 24. Image-guided ablation in the thorax Erica S. Alexander and Damian E. Dupuy; Part VIII. Organ-Specific Cancers - Musculoskeletal: 25. Percutaneous ablation of painful metastases involving bone Matthew R. Callstrom and A. Nicholas Kurup; 26. Cementoplasty and musculoskeletal interventions Sean Tutton and Alexis Kelekis; Part IX. Organ-Specific Cancers - Prostate: 27. Prostate ablations Francois Cornelis, Jeremy C. Durack, Behfar Ehdaie, J. Coleman and Stephen B. Solomon; Part X. Specialized Interventional Techniques in Cancer Care: 28. Vascular access: venous and arterial ports Thierry de Baère and Eric Desruennes; 29. Palliative care and symptom management Drew A. Rosielle, Melissa Atwood, Sean Marks and William S. Rilling; 30. CT-guided neurolysis for cancer-related abdominal and pelvic pain Ashraf Thabet; 31. Palliative procedures for ascites and effusion Hooman Yarmohammadi.