Brucella Melitensis: Identification and Characterization of Potential Drug Targets

ISBN-13: 9780323856812 / Angielski / Miękka / 2021

Jangampalli Adi Pradeepkiran; S. B. Sainath

Spis treści

1. Introduction to Brucellosis 2. Identification and characterization of vaccine targets for Brucella melitensis through in silico approaches 3. Computational modeling and evaluation of best potential drug targets through comparative modeling 4. Molecular docking and dynamics simulations of novel drug targets 5. In silico validation and ADMET analysis for best lead molecules 6. Summary and Conclusions

O autorze

Jangampalli Adi Pradeepkiran is Post-Doctoral Research Associate in Internal Medicine at the Texas Tech University Health Sciences Center, USA. He has over a decade's experience in designing and executing bioactive molecules, and in computational biology reaction mechanisms. His research interests include microbiology, immunology, therapeutics, and process research in cell cultures and animal models, among other areas. He has published over 30 research papers. S.B. Sainath is Assistant Professor in the Biotechnology Department at Vikrama Simhapuri University in the Nellore district of Andhra Pradesh, India. He obtained his PhD from Sri Venhateswara University in India, and has held positions at DST-SERB, and a Post-Doctoral Fellowship from the Foundation of Science and Technology, at the University or Porto in Portugal. His research focuses on nuclear signaling mechanisms across metazoan phyla. He has published four books, and over 30 articles.