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Recombinant proteins and polypeptides continue to be the most important class of biotechnology-derived agents in today's pharmaceutical industry. Over the past few years, our fundamental understanding of how proteins degrade and how stabilizing agents work has made it possible to approach formulation of protein pharmaceuticals from a much more rational point of view.

This book describes the current level of understanding of protein instability and the strategies for stabilizing proteins under a variety of stressful conditions.

As one of the first American literary expatriates and as a central figure in both the Imagist and the Fugitive-Agrarian movements, John Gould Fletcher occupies a special place in modern literary history. In "The Autobiography of John Gould Fletcher" (first published in 1937, one year before he won the Pulitzer Prize for Poetry), Fletcher relates in rich detail the events of an astonishingly productive literary life that brought him recognition on both sides of the Atlantic. His narrative displays an acutely perceptive insider s view of the vibrant English and American literary scenes...

Stith Thompson (1885 1976), often called the father of U.S. folklore, completed A Folklorist s Progress in 1956. This reflection on his life leads the reader on a journey from his birthplace in Kentucky to the universities of Wisconsin, Harvard, California, Texas, and finally Indiana University. Throughout his career he interacted with scholars throughout the world. His life story reveals his influence on the direction of American folklore scholarship in this century. His influence moved the study of folklore from a romantic approach to a "scientific" approach. He helped establish folklore...

Project Mercury ran from 1959 through 1963, put the first American in space, and defined NASA's manned space flights to come, from Gemini through Apollo. In We Seven, first published in 1962, the astronauts including Scott Carpenter, Gordon Cooper, John Glenn, Virgil Grissom, Walter Schirra, Alan Shepard, and Donald Slayton--take you behind the scenes of this pioneering program--even into the space capsules themselves.

Featuring fascinating firsthand accounts...