Early Detection of Cardiac Rejection

ISBN-13: 9783639172874 / Angielski / Miękka / 2009 / 116 str.

Hsun-Hsien Chang

Opis

Heart transplantation is the preferred treatment for patients suffering from end-stage cardiac diseases. Early detection of acute rejection is central to saving heart transplants and lasting the patients lives. Since rejection in early stage occurs locally, traditional methods such as electrocardiogram and biopsy fail to localize regional myocardial rejection in early stage. In contrast, MRI holds the promise to unveil the volumetric functional landscape in the heart. Among many MRI protocols, tagged MRI can assist cardiac motion tracking, and contrast-enhanced MRI can help localize immune cells infiltrating abnormal myocardial tissues. The book starts with the fundamental principles of MRI protocols, followed by the state-of-the-art MR image processing techniques that can detect regional functional loss in early stage.

O autorze

Hsun-Hsien Chang is a bioinformatics researcher in Children's
Hospital Informatics Program, Harvard Medical School. His
research interests lie at the intersection of information
science and biology, with the twin objectives of
understanding the information theory in biology and of
developing novel analysis tools for biological studies.