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Cp20 is a neuronal protein involved in the molecular mechanisms of synaptic plasticity. Cp20 was first identified in the CNS of the marine snail Hermissenda, which can be trained to learn an association between visual and vestibular stimuli in a Pavlovian conditioning procedure. Upon learning, cp20 is phosphorylated in a few defined neurons of Hermissenda, and inhibits the Ca2+-dependent K+ channels. This results in an increase in membrane resistence and therefore a hyperexcitability of the neuronal pathway. Similar biochemical mechanisms have been proposed to underlie memory in higher...

In Computational Neuroanatomy: Principles and Methods, the path-breaking investigators who founded the field review the principles and key techniques available to begin the creation of anatomically accurate and complete models of the brain. Combining the vast, data-rich field of anatomy with the computational power of novel hardware, software, and computer graphics, these pioneering investigators lead the reader from the subcellular details of dendritic branching and firing to system-level assemblies and models.

In Computational Neuroanatomy: Principles and Methods, the path-breaking investigators who founded the field review the principles and key techniques available to begin the creation of anatomically accurate and complete models of the brain. Combining the vast, data-rich field of anatomy with the computational power of novel hardware, software, and computer graphics, these pioneering investigators lead the reader from the subcellular details of dendritic branching and firing to system-level assemblies and models.

This book constitutes the refereed proceedings of the International Conference on Brain and Health Informatics, BHI 2016, held in Omaha, USA, in October 2016.

The 37 revised full papers, including two workshop papers from BAI 2016, presented were carefully reviewed and selected for inclusion in the book. The papers are organized in topical sections on cognitive and computational foundations of brain science; investigations of human information processing systems; brain big data analytics, curation and management; new methodologies for brain and mental health; brain-inspired...