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Muscle disease represents an important health threat to the general population. Unlike diseases affecting other tissues/organs, therapeutic options are quite limited for many inherited muscle diseases such as Duchenne muscular dystrophy. There is essentially no cure. Gene therapy holds great promise to correct the genetic defects and eventually achieve full recovery in these diseases. Significant progresses have been made in the field of muscle gene therapy over the last few years. A variety of new strategies, such as exon-skipping and RNAi, have greatly expanded the scope of muscle gene...

This book provides a detailed study of several types of control problems in multi-agent systems, including consensus, output regulation, containment, and formation problems. The research on collaborative control of multi-agent systems has attracted engineers and scientists from various disciplines such as control, mathematics, artificial intelligence, and computer engineering. This book proposes a control strategy based on adaptive triggering mechanism and establishes a basic energy-saving framework; it also proposes an adaptive learning rate to replace fixed weights, ensuring that the...

This book starts from the classic recommendation algorithms, introduces readers to the basic principles and main concepts of the traditional algorithms, and analyzes their advantages and limitations. Then, it addresses the fundamentals of deep learning, focusing on the deep-learning-based technology used, and analyzes problems arising in the theory and practice of recommender systems, helping readers gain a deeper understanding of the cutting-edge technology used in these systems. Lastly, it shares practical experience with Microsoft 's open source project Microsoft Recommenders. Readers...