Cardioprotective Effect of Combination of Enalapril and Fenofibrate

ISBN-13: 9783845420707 / Angielski / Miękka / 68 str.

Firoz Momin; Nilofar Naikwade; Tabassum Shikalgar

Opis

Doxorubicin (Adriamycin) is a well known anticancer drug used to cause cardiac damage in rats. In this book, combination of Enalapril and fenofibrate were assessed for cardioprotective effect. Parameters evaluated were ECG, blood pressure, serum markers viz. LDH, CK-MB, SGPT, SGOT, ALP, serum urea and serum creatinine. Tissue antioxidant markers viz. CAT and SOD, lipid peroxidation (MDA) for heart, liver and kidney and histopathological study of heart, liver and kidney. Parameters such as body weight, organ weight (heart, liver and kidney) and organ/body weight ratio were also evaluated.

O autorze

Mr. Firoz Noor Mohammed Momin is a research scholar in the field of Pharmacology. He has done his Masters of Pharmacy (Pharmacology) from Appasaheb Birnale College of Pharmacy, Sangli (Shivaji University, Kolhapur, MS, India). He has worked on 5 research papers related to Doxorubicin induced cardiotoxicity under the guidance of Dr. Nilofar Naikwade