Emulsomes: A rising tool against visceral leishmaniasis

ISBN-13: 9783659330049 / Angielski / Miękka / 2013 / 120 str.

Gupta Swati;Vyas Suresh P;Dube Anuradha

Opis

Leishmaniasis is a zoonotic infection caused by the protozoa belonging to the genus Leishmania. Current antimicrobials of leishmaniasis suffer the disadvantages of toxicity to parenchymal cells and heart, emergence of drug resistant strains and prolonged course of treatment. The rational approach to the problem requires that drugs should be targeted to the macrophages in such a way that the interaction of the free drug with non-target tissues could be minimized. The book describes the development and evaluation of emulsomes (novel nano drug delivery system) for selective and targeted delivery of Amphotericin B to macrophages of the liver and spleen for the effective chemotherapy of visceral leishmaniasis.

O autorze

Swati Gupta (M.Pharm, Ph.D) has nearly ten years of research experience and presently working as Associate Professor in ISF College of Pharmacy, Moga India. Dr Gupta has over twenty five publications, published in journals of international repute. Her research interests include drug delivery systems, drug targeting and molecular pharmaceutics.