Mechanisms of Cell Death and Opportunities for Therapeutic Development

ISBN-13: 9780128142080 / Angielski / Miękka / 2021 / 660 str.

Diaqing Liao

Spis treści

1. An overview of cell death in health and disease 2. Cell death:machinery and regulation 3. Molecular mechanisms of cell death: A brief overview 4. Major methods and technologies for assessing cell death 5. Proteotoxicity and endoplasmic reticulum stress-mediated cell death 6. Protein phase separation in cell death and survival 7. Therapeutics targeting the BCL-2 pathway 8. Ferroptosis: lipids, iron, cellualar defese mechanisms and opportunities for drug development

O autorze

Diaing Liao has extensive experience, over twenty years, in research and teaching related to topics of cell death. He has been the course director of a graduate level course "Apoptosis” for over ten years at University of Florida. Dr. Liao's research has focused on mechanisms underlying cancer biology, epigenetic regulation and drug discovery. His lab has contributed numerous original publications on cellular and viral regulators of cell death and signalling pathways.