The new heteroaryl compounds having 5-HT1A / 5-HT2A affinity

ISBN-13: 9783659694882 / Angielski / Miękka / 2015 / 140 str.

Dhanawat Minakshi;Sharma Gaurav Kumar;Shrivastava Sushant Kumar

Opis

The ultimate goal of the experiments conducted in the realm of this work was to design, synthesize, characterize some novel heterocyclic compounds comprising of 4-arylpiperazine/ aniline moiety linked to a terminal cyclic amide through a spacer followed by their biological evaluation and molecular modeling studies as anti-convulsants and evaluation of their interactions with 5-HT1A and 5-HT2A receptor subtypes as agonist/antagonist through validated in vivo behavioral models.

O autorze

Dr.Meenakshi dhanawat,PhD(Pharmaceutical Chemistry),Department of Pharmaceutics,IIT-BHU Varanasi,U.P.,Assistant prof. And HODDepartment of Pharmacy ,Mewar University, (Gangrar)Chittorgarh, Rajasthan