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Designed to be a practical handbook on clinical trial management in these key therapeutic areas, 'Clinical Trials in Rheumatoid Arthritis and Osteoarthritis' is aimed at principal investigators pharmaceutical physicians and other pharmaceutical staff involved in the design, conduct and monitoring of these increasingly complex diseases.

In the last several years a new classes of biologic agents have emerged and changed the treatment paradigm for patients, not only with classically defined rheumatoid arthritis, but also with other related diseases such as ankylosing...

This volume describes and evaluates the major current research developments in the ocean sciences. Topics include advances in measuring ocean phenomena from space, DEGREESIin situ DEGREESR instruments, and the development of fully integrated observing systems that allow investigators to take environmental snapshots of areas that must be monitored in order to protect property and save lives. The authors emphasize that today's successful oceanographic programs rely on multidisciplinary, integrated, and task-organized teams of varying professionals, marine technicians, and...