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The introduction of PSA testing into clinical practice has revolutionised the diagnosis and management of prostate cancer, although much debate surrounds the value of PSA testing. Despite the lack of definitive evidence, there is widespread use of PSA screening in asymptomatic men, with aggressive investigation and treatment recommended. This has undoubtedly led to overdiagnosis and overtreatment of some men with prostate cancer. This book summarises the basis and clinical aspects of PSA testing and prostate cancer diagnosis. Additionally, data from a unique population-based...

This book offers a fresh assessment of George W. Bush's foreign policies. It is not designed to offer an evaluation of the totality of George W. Bush's foreign policy. Instead, the analysis will focus on the key aspects of his foreign and security policy record, in each case considering the interplay between principle and pragmatism. The underpinning contention here is that policy formulation and implementation across Bush's two terms can more usefully be analysed in terms of shades of grey, rather than the black and white hues in which it has often been painted. Thus, in some key policy...