Structural Biology in Immunology: Structure/Function of Novel Molecules of Immunologic Importance

ISBN-13: 9780128033692 / Angielski / Miękka / 2018 / 186 str.

Chaim Putterman; David Cowburn; Steven Almo

Spis treści

1. Organization of Immunological Synapses and Kinapses 2. Principles of Protein Recognition by Small T-Cell Adhesion Proteins and Costimulatory Receptors 3. Synthetic Antibody Engineering: Concepts and Applications 4. Natural Killer Cell Receptor 5. Structure-Function in Antibodies to Double-Stranded DNA 6. The Role of the Constant Region in Antibody-Antigen Interactions: Redefining the Modular Model of Immunoglobulin Structure

O autorze

Dr. Chaim Putterman is Professor of Medicine, Microbiology and Immunology, and Chief of the Division of Rheumatology, Albert Einstein College of Medicine, he is a board certified rheumatologist in Bronx, New York. He is currently licensed to practice medicine in New York and New Jersey. He is affiliated with Burke Rehabilitation Hospital and is a Chief; Professor at Rheumatology; Microbiology & Immunology https://www.doximity.com/pub/chaim-putterman-md. He is editorial board member of the Elsevier journals: Clinical Immunology, Autoimmunity Reviews, and the Journal of Autoimmunity. His H= 30 Dr. David Cowburn is Professor in the Departments of Biochemistry and Physiology & Biophysics at the Albert Einstein College Of Medicine, David Cowburn's research centers on the application of structural biology, and particularly, nuclear magnetic resonance (NMR), to biological problems. He was a faculty member at Rockefeller University 1973-2000, and served as the start-up President and CEO of the New York Structural Biology Center, 2000-2010. http://cowburnlab.org/DavidCowburnFullBio.pdf. Dr. Steven Almo is a Professor in the Departments of Biochemistry and Physiology and Biophysics. Dr. Almo is a world renowned expert in structural biology and crystallography. He directs Einstein research as part of the NIGMS's Protein Structure Initiative (PSI), a decade-long federal, university and industry effort aimed at dramatically reducing the costs and lessening the time it takes to determine a three-dimensional protein structure from its DNA sequence. He is Director of Structural Proteomics, New York Structural Biology Center, November 2006-present And Director, Albert Einstein Macromolecular Therapeutic Development Facility 2007-present. He is member of the American Society for Cell Biology and American Crystallographic Association