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Esau and Jacob is the last of Machado de Assis's four great novels. At one level it is the story of twin brothers in love with the same woman and her inability to choose between them. At another level, it is the story of Brazil itself, caught between the traditional and the modern, and between the monarchical and republican ideals. Instead of a heroic biblical fable, Machado de Assis gives us a story of the petty squabbles, conflicting ambitions, doubts, and insecurities that are part of the human condition.

This book constitutes the refereed proceedings of the 15th European Conference on Genetic Programming, EuroGP 2012, held in Malaga, Spain, in April 2012 co-located with the Evo* 2012 events. The 18 revised full papers presented together with 5 poster papers were carefully reviewed and selected from 46 submissions. The wide range of topics in this volume reflects the current state of research in the field, including different genres of GP (tree-based, grammar-based, Cartesian), theory, novel operators, and applications.