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This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding...

Although governmental commissions are not the only available source of nonpartisan investigation and policy advice, their prestige, scale of operation, and national importance establish the commission as a unique political body. This volume provides both general discussions of commission communication and specific analyses of commissions.

Part One considers definitional and functional issues inherent in commission studies, and takes up such concerns as the constraints under which these entities operate. Part Two is devoted to case studies of historically, politically, or socially...