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This book is the story of an inherited blood disease Cooley's anemia or beta thalassemia. Cooley's anemia is a severe and potentially fatal anemia that affects millions of people worldwide. Written by a world-recognized expert on the disease who has contributed greatly to the scientific understanding of the pathophysiology of this human hemoglobin disorder, the book describes the emotional and medical impact of the disease on patients and their families. It also summarizes the research on the disease at the level of the genes, DNA, RNA, and proteins. In addition, it also includes chapters on...

This book describes the life and times of a physician-scientist over the last half-century. Part One is about the author's struggle with colon cancer and the lessons he learnt from the experience; Part Two is about his life growing up, the pretzel bakery, his family, being educated at Bronx Science, Columbia College, Harvard Medical School, and his medical training at the Boston City Hospital and the NIH. Part Three, the major portion of the book, describes the author's experiences as a practicing physician and hematologist at Columbia-Presbyterian Medical Center over 40 years. It also...