Pyridine Derivatives as Anti-malarial Agent : Design, Synthesis and Biological Screening

ISBN-13: 9783659443794 / Angielski / Miękka / 2013 / 72 str.

Ashenafi Damtew Mamuye; Adnan A. Bekhit; Ariaya Hymete

Opis

The process of discovering a drug is critical to the society s progress in medical care and quality of life. Antimalarial drug resistance is one of the biggest challenges of malaria control today. Therefore, it is necessary to seek for new drugs that attack crucial targets in the malarial pathogen in order to combat and relieve this tremendous prevalence. Thus, in an effort to discover novel antimalarial agents; new compounds were designed in the present work by incorporating some pharmacophoric assemblies to the pyridine nucleus.

O autorze

Ashenafi Damtew Mamuye, BSc in applied chemistry at University of Gondar (2006), Ethiopia; MSc in Medicinal Chemistry at Addis Ababa University (2009), Ethiopia; Chemical Science and Technologies PhD student in Sassari University (2011-), Italy.