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Cancer is initiated by activation of oncogenes or inactivation of tumor suppressor genes. Mutations in the K-ras proto-oncogene are responsible for 10-30% of adenocarcinomas. Clinical Findings point to a wide variety of other cancers contributing to lung cancer incidence. Such a scenario makes identification of lung cancer difficult and thus identifying its mechanisms can contribute to the society. Identifying unique conserved patterns common to contributing proto-oncogenes may further be a boon to Pharmacogenomics and pharmacoinformatics. This calls for ab initio/de novo drug discovery...

Diverse Early Childhood Education Policies and Practices explores issues in early childhood education and teacher preparation in five Asian countries: India, Singapore, China, Sri Lanka, and the Maldives. Some observed classrooms in these countries reflect influences that are simultaneously indigenous and colonial, local and global. By highlighting the diverse and often hybrid classroom pedagogies at work in these 21^st century Asian classrooms, the discussions in this book take into consideration the influence of globalization on local policies and practices, and the...

Afghanistan is one of many South Asian countries appearing in daily headlines, as it attempts to rebuild its society, including its educational system, after decades of war. Sri Lanka, devastated by the tsunami of 2004, and parts of Pakistan and Northern India, coping with the aftereffects of a major earthquake, are also also struggling for teachers, classrooms, supplies, and a sense of normalcy for their students. This volume, part of the Schooling Around the World series, provides readers with a history and survey of education in eight of the region's countries. It examines the Primary,...

South Asia today is among the most unstable regions in the world, riddled by both intra- and inter-state conflict. This book presents a comprehensive technical analysis of the trade-conflict relationship within the region, and explores how South Asia demonstrates underperformance of its potential for economic integration.

Using the gravity model framework, the book highlights quantitative estimates of the cost of conflict in terms of loss of trade for South Asia. Other variables representative of political and economic regimes are also included to make the model...