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Glycyrrhizin (GL), the well-known sweet saponin of licorice, has been used as a food-additive and as a medicine. Its aglycone, glycyrrhetinic acid (GA) showed antiinflamatory, antiulcer and antiviral properties. GA is now produced form GL by acid hydrolysis. However, it is difficult to obtain GA in a good yield by this method, because many by- products are also produced. To produce GA from GL, we have screened microorganisms for activity to hydrolyze GL. Then, the selected strain was subjected to different studies concerning the effect of some physiological and biochemical...