Fortschritte Der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products

ISBN-13: 9783709193396 / Angielski / Miękka / 2012 / 216 str.

J. Bermejo Barrera; H. J. M. Gijsen; A. G. Gonzales

Opis

Contents: A.G. Gonzalez and J. Bermejo Barrera: Chemistry and Sources of Mono- and Bicyclic Sesquiterpenes from Ferula Species. - G. Prota: The Chemistry of Melanins and Melanogenesis. - H.J.M. Gijsen, J.B.P.A. Wijnberg, and Ae. de Groot: Structure, Occurrence, Biosynthesis, Biological Activity, Synthesis, and Chemistry of Aromadendrane Sesquiterpenoids. The volumes of this classic series, now referred to simply as "Zechmeister after its founder, L. Zechmeister, have appeared under the Springer Imprint ever since the series inauguration in 1938. The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in his field and provides a comprehensive and up-to-date review of the topic in question. Addressed to biologists, technologists, and chemists alike, the series can be used by the expert as a source of information and literature citations and by the non-expert as a means of orientation in a rapidly developing discipline.

Spis treści

Chemistry and Sources of Mono- and Bicyclic Sesquiterpenes from Ferula Species.- I. Introduction.- II. Biosynthetic Relationships.- III. Extraction and Isolation.- IV. Determination and Structural Types.- V. Monocyclic Sesquiterpenes.- VI. Bicyclic Sesquiterpenes.- 1. Bicyclic Alcohol Esters with a Hydroxy Group at C-10.- 2. Bicyclic Alcohol Esters with a Hydroxy Group at C-6.- VII. Other Sesquiterpenoids from Ferula Species.- VIII. Common Ester Side Chains in Sesquiterpenes from Ferula Species.- References.- The Chemistry of Melanins and Melanogenesis.- I. Introduction.- II. The Tangled Yarn of Melanin Research.- A. The Early Studies.- B. Melanogenesis in Vitro.- C. Melanogenesis in Vivo.- III. Note on Terminology.- IV. Eumelanins.- A. Protein Content.- B. Isolation and Analysis.- C. Synthetic Melanins.- D. Free Radicals and Redox Properties.- E. Carboxylic and Phenolic Groups.- F. Chemical Degradation.- G. Biomimetic and Biosynthetic Studies.- 1. Rearrangement of Dopachrome.- a. Mechanism of Reaction.- b. Regulatory Factors.- 2. Polymerization of Eumelanin Precursors.- a. 5,6-Dihydroxyindole.- b. 5,6-Dihydroxyindole-2-Carboxylic Acid.- V. Pheomelanins and Related Pigments.- A. Trichochromes.- B. Gallopheomelanins.- 1. Isolation and General Properties.- 2. Gallopheomelanin-1.- C. Biosynthetic Studies.- 1. The Pigment Precursors.- 2. Occurrence and Origin of Cysdopas.- 3. 1,4-Benzothiazinylalanines.- VI. Overview of Reaction Pathways.- Abbreviations.- References.- Structure, Occurrence, Biosynthesis, Biological Activity, Synthesis, and Chemistry of Aromadendrane Sesquiterpenoids.- 1. Structure and Occurrence.- 2. Biosynthesis.- 3. Biological Activity.- 4. Total Syntheses of Aromadendranes.- 5. Aromadendranes as Starting Materials in the Synthesis of Sesquiterpenes.- References.- Author Index.