Congenital Adrenal Hyperplasia: A Comprehensive Guide

ISBN-13: 9780128114834 / Angielski / Miękka / 2017 / 504 str.

London Kathy (Chair CAHISUS Support and Information Group

Opis

Congenital Adrenal Hyperplasia: A Comprehensive Guide addresses how hydrocortisone works, what can go wrong, and how to correct it, also explaining why the timing of doses and measurement of cortisol from a dose is extremely important. The book provides an in-depth analysis of this disorder for pediatric endocrinologists and primary care providers, allowing them to help patients with an updated model of care and appropriate treatment. Patients and family members will benefit from the trend-forward information that will empower them to approach their healthcare providers with the expectation of receiving individualized care and treatment for this disorder.

• Outlines the basics of congenital adrenal hyperplasia and its interrelation with hormones and bodily functions
• Presents the known cognitive and emotional aspects of the disease
• Reviews multidisciplinary management as well as post-treatment management of the disease

Spis treści

Section One: Congenital adrenal hyperplasia-introduction1. Physiology of the Adrenal Glands: How Does It Work?2. How Males and Females Develop3. Genetics of Congenital Adrenal Hyperplasia4. Common Forms of Congenital Adrenal Hyperplasia5. Other Blocks in the Pathway Causing Congenital Adrenal Hyperplasia6. Growth7. Puberty8. Biochemical Tests Used for Diagnosis

Section Two: When things go wrong in congenital adrenal hyperplasia9. Monitoring Long Term Outcomes10. Growth11. When Things Go Wrong With Puberty12. When Things Go Wrong-Weight, Diabetes and Hypertension13. When Things Go Wrong-Bone Density and Osteoporosis14. Fertility15. Sleep and Mood Alterations16. Abdominal, Skin and Other Problems

Section Three: Treatment for congenital adrenal hyperplasia17. History of Steroid Development18. Glucocorticoid Treatment19. Glucose and Cortisol20. Hydrocortisone21. Dosing and the Circadian Rhythm22. Cortisol and 17-Hydroxyprogesterone23. Using Profiles to Assess Cortisol Replacement24. Monitoring Hydrocortisone Therapy25. Other Hormones and Their Roles26. Missing a Dose of Hydrocortisone27. Intravenous, Intramuscular and Other Forms of Hydrocortisone28. The Pump Method for Achieving a Normal Circadian Cortisol Replacement29. Stress Dosing for Sick Days, Surgery, Exams and Exercise30. Practical Information Emergency Kit and School Information31. Other Treatments for Congenital Adrenal Hyperplasia-Prednisolone, Dexamethasone and Adrenalectomy32. Fludrocortisone 9 Alpha-Fludrocortisone33. Travel and Time Zones34. Thinking Through Blood Results-A Quiz35. Discussing the Emotional Aspects of Living With Congenital Adrenal HyperplasiaAppendix 1. Converting System International (SI) Blood Measures Into North American Values or Conventional UnitsAppendix 2. List of Abbreviations

O autorze

Peter Hindmarsh is Professor of Pediatric Endocrinology at University College London and Consultant in Pediatric Endocrinology and Diabetes at University College London Hospitals and Great Ormond Street Hospital for Children. Currently, he is applying Chronic Care Models to the delivery of care for patients with Congenital Adrenal Hyperplasia. His research interests are in the physiology and pharmacology of drugs used to manage Congenital Adrenal Hyperplasia and novel ways of delivery Hydrocortisone using pump therapy to mimic the circadian rhythm. As the parent of a young adult with Salt Wasting Congenital Adrenal Hyperplasia, Kathy Geertsma became Chair of the Congenital Adrenal Hyperplasia Parent and Support Group. She has extensive contact with parents and patients from all over the world who struggle with confirming a CAH diagnosis and getting proper treatment. As a result, she offers a unique perspective about how practitioners can better serve the needs of their patient population.