Biosensors: Theory and Applications

ISBN-13: 9780877629757 / Angielski / Twarda / 1995 / 232 str.

Donald G. Buerk

Opis

An overview of the basic theories of operation for a number of specific types of biosensor transducers that have been investigated, and surveys some of the many applications of the various biological elements that are described. Buerk (ophthalmology and environmental medicine, U. of Pennsylvania) fo

Spis treści

Each chapter ends with a section of references
Introduction
o Brief Historical Background
o Early Applications of Noble Metal Electrodes
o Early Optical Methods
o Ideal Biosensor Characteris-tics

Basic Electrochemical Principles
o Electrochemical Cells
o Oxide-Reduction Reactions
o Voltage and Current Standard Conditions
o Steady State Voltammogram
o Transient Responses
o Asymptotic Solutions and Data Transformations
o Galvanostatic Response
o Coulostatic Response

Electrochemical Transducers in Biology and Medicine
o Glass pH Electrodes
o Metal Oxide pH Electrodes
o pH-Sensitive Mem-branes
o Oxygen Electrodes
o Carbon Dioxide Electrodes
o Hydrogen Gas Electrodes
o Hydrogen Peroxide Electrodes
o Carbon Surface Electrodes
o Ion-Sensitive Electrodes
o Other Electrochemical Detection Methods
o Clinical Applications of Electrochemical Transducers

Enzyme-Based Electrochemical Biosensors
o Enzyme Biocatalysis Theory
o Immobilization Techniques
o Glucose Biosensor
o Blood Glucose Monitoring
o Industrial Glucose Monitoring
o Urea Biosensor
o Alcohol Biosensors
o More Single Enzyme Biosensors
o Multiple Enzyme Biosensors
o Carbon Electrode Enzyme-Based Biosen-sors
o Organic Phase Enzyme Biosensors
o Alternate Electron Donors

Fabrication and Miniaturization Techniques
o Microelectrodes
o Enzyme Modifi ed Microelectrodes
o Miniaturized Arrays
o Semiconductor Needle
o ENFET Biosensors

Optical Technology
o Principles of Optical Measurements
o Absorption Spectroscopy
o Refl ec-tance Spectroscopy
o Fluorescence
o Phosphorescence
o Oxyhemoglobin and Oximetry
o Digital Image Processing
o Optodes
o Optical Waveguides
o Light-Addressable Potentiometric Sensor

Miscellaneous Transducer Technologies
o Enzyme-Based Calorimetry
o Piezoelectric M

O autorze

Buerk, Donald G.