Bioinformatics for Beginners: Genes, Genomes, Molecular Evolution, Databases and Analytical Tools

ISBN-13: 9780124104716 / Angielski / Twarda / 2014 / 238 str.

Supratim Choudhuri

Opis

Bioinformatics for Beginners: Genes, Genomes, Molecular Evolution, Databases and Analytical Tools provides a coherent and friendly treatment of bioinformatics for any student or scientist within biology who has not routinely performed bioinformatic analysis. The book discusses the relevant principles needed to understand the theoretical underpinnings of bioinformatic analysis and demonstrates, with examples, targeted analysis using freely available web-based software and publicly available databases. Eschewing non-essential information, the work focuses on principles and hands-on analysis, also pointing to further study options.

• Avoids non-essential coverage, yet fully describes the field for beginners
• Explains the molecular basis of evolution to place bioinformatic analysis in biological context
• Provides useful links to the vast resource of publicly available bioinformatic databases and analysis tools
• Contains over 100 figures that aid in concept discovery and illustration

Spis treści

1. Fundamentals of Genes and Genomes 2. Fundamentals of Molecular Evolution3. Genomic Technologies4. The Beginning of Bioinformatics 5. Data, Databases, Data Format, Database Search, Data Retrieval Systems and Genome Browsers6. Sequence Alignment and Similarity Searching in Genomic Databases: Blast and Fasta7. Additional Analyses Involving Nucleic Acid Sequences8. Additional Analyses Involving Protein Sequences9. Phylogenetic Analysis

O autorze

Dr. Supratim Choudhuri is a toxicologist at the Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration. Dr. Choudhuri has extensively published in the fields of molecular toxicology, metabolism, genomics, and epigenetics. He has previously edited a book, titled Genomics: Fundamentals and Applications with a colleague Dr. David B. Carlson.